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Dermatopathology IHC portfolio

Skin cancer is one of the most preventable cancers and highly treatable when found early

Dermatopathology panel

Exceptional antibodies
 

Confidence and convenience

Pre-diluted, optimized antibodies come ready to use in dispensers that are specially designed for use on the VENTANA BenchMark IHC/ISH series of instruments. Ventana antibodies provide a convenient IHC solution for both routine and innovative diagnostic tests.
 

Fully automated, direct immunolfourescence staining

For autoimmune disorders and other inlfammatory processes Roche offers FITC- labeled antibodies against: C3, fibrinogen, IgA, IgG and IgM
 

Additional derm-related markers to meet a broad range of diagnostic needs including:
  • Squamous cell vs. basal cell carcinoma
  • Cutaneous lymphomas
  • Dermatofibrosarcoma protuberans (DFSP)
  • Merkel cell carcinoma
  • Sebaceous carcinoma
     
Comprehensive melanoma panel

Melanoma is a malignancy of melanocytes and histology is the gold standard for distinguishing malignant cells from benigncells. IHC in this context is useful to establish melanocytic lineage (melanoma), versus other lineages (carcinoma, sarcoma, B- or T-cell lymphoma).

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Featured Assays

SOX-10 (SP267) Rabbit Monoclonal Primary Antibody

SOX-10 (SP267) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the detection of the SOX-10 protein in formalin-fxed, paraffin-embedded tissue stained on BenchMark immunohistochemical (IHC/ISH) automated slide stainers. SOX-10 is a nuclear transcription factor that participates in neural crest development and in the specification and differentiation of cells of melanocytic lineage.2

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CONFIRM anti-MART-1/melan A (A103) Mouse Monoclonal Primary Antibody

CONFIRM anti-MART-1/melan A (A103) Mouse Monoclonal Primary Antibody is a mouse monoclonal antibody (IgG1) directed against melan A. Positive staining may aid in the classification of melanoma.2,3

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Anti-PRAME (EPR20330) Rabbit Monoclonal Primary Antibody

The anti-PRAME (EPR20330) Rabbit Monoclonal Primary Antibody detects the overexpression of the tumor-associated antigen, PReferentially expressed Antigen in MElanoma (PRAME), in formalin-fixed paraffin embedded tissue. Positive staining may aid in the differentiation of benign versus malignant melanocytic lesions.4,5

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Sensitive and speciifc detection systems

Roche offers ready-to-use detection systems in red and brown chromogens with the ability to perform dual chromogen staining that is compatible with any species combination of mouse and rabbit primary antibodies. The fexibility of our detection systems can help you achieve consistent, high-quality results to meet your IHC testing needs.

ultraView Universal Alkaline Phosphatase

ultraView Universal Alkaline Phosphatase Red Detection Kit and  ultraView Universal DAB Detection Kit

ultraView detection systems are leading-edge multimer-technology based kits 
suitable for use with both mouse and rabbit primary antibodies
ultraView chemistry provides crisp morphology, enabling the sensitive and 
specific visualisation of the targeted antigen. The kits are biotin-free, thus eliminating non-specific staining caused by endogenous biotin.

ultraView Universal Alkaline Phosphatase Red Detection Kit

ultraView Universal DAB Detection Kit

Optiview DAB IHC Detection Chemistry

OptiView DAB IHC Detection Chemistry

By increasing the numbers of HRP enzymes at each primary antibody site, 
OptiView DAB IHC detection provides unparalleled signal intensity, empowering
you to achieve the level of intensity you desire, even for low-expressing antigens.
Our synthetic, non-endogenous hapten system virtually eliminates background
 even as signal intensity increases.

OptiView DAB IHC Detection Kit

Flexible dual chromogen staining 

Endless possibilities

  • Greater context for diagnosis with brown and red chromogens
  • Simpler, faster interpretation
  • Compatible with any species combination of mouse and rabbit primary antibodies (mouse-mouse, rabbit-rabbit, rabbit-mouse)
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Single stain — Dual stain — Single stain

PAX-5 (790-4420) and CD 3 (790-4341), tonsil 30x

PAX-5 (790-4420) and CD 3 (790-4341), tonsil 30x

Ki-67 (790-4286) and MART-1/melan- A (790-2990), skin 30x

Ki-67 (790-4286) and MART-1/melan- A (790-2990), skin 30x

CD45 (760-2505) and MART-1/melan-A (790-2990), skin 30x

CD45 (760-2505) and MART-1/melan-A (790-2990), skin 30x

BENCHMARK, CONFIRM, OPTIVIEW, ULTRAVIEW and VENTANA are trademarks of Roche.

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